網站地圖 聯系我們搜索內部網English | 中國科學院
首頁 所況簡介 機構設置 科研隊伍 科學研究平臺 院地合作 黨群園地 國際交流 博士后 研究生教育 信息公開
科研進展
成果報道
最新重要論文(影響因子PNAS及以上)
發表論文數據庫
所級學術報告
科學成果
發表論文
專著
專利
獲獎
專題
所史叢書
所慶專輯
建所50周年畫冊
現在位置:首頁 > 科研進展 > 最新重要論文(影響因子PNAS及以上)
SpatialDB: a database for spatially resolved transcriptomes, Nuleic Acids Res, 12 Nov 2019
2019-11-12 | 【     】【打印】【關閉

Nucleic Acids Research12 November, 2019,DOI:https://doi.org/10.1093/nar/gkz934

SpatialDB: a database for spatially resolved transcriptomes

Zhen Fan, Runsheng Chen, Xiaowei Chen

Abstract

Spatially resolved transcriptomic techniques allow the characterization of spatial organization of cells in tissues, which revolutionize the studies of tissue function and disease pathology. New strategies for detecting spatial gene expression patterns are emerging, and spatially resolved transcriptomic data are accumulating rapidly. However, it is not convenient for biologists to exploit these data due to the diversity of strategies and complexity in data analysis. Here, we present SpatialDB, the first manually curated database for spatially resolved transcriptomic techniques and datasets. The current version of SpatialDB contains 24 datasets (305 sub-datasets) from 5 species generated by 8 spatially resolved transcriptomic techniques. SpatialDB provides a user-friendly web interface for visualization and comparison of spatially resolved transcriptomic data. To further explore these data, SpatialDB also provides spatially variable genes and their functional enrichment annotation. SpatialDB offers a repository for research community to investigate the spatial cellular structure of tissues, and may bring new insights into understanding the cellular microenvironment in disease. SpatialDB is freely available at https://www.spatialomics.org/SpatialDB.

文章鏈接:https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz934/5622703

 

 

 

評 論
          
版權所有:中國科學院生物物理研究所     京ICP備05002792號 京公網安備 110402500011 號
地址:北京市朝陽區大屯路15號(100101) 電話:010-64889872
意見反饋聯系人:侯文茹 電子郵件:[email protected]
彩票开奖直播 明天股票涨还是跌 天津港股票趋势 3d一的对应两码是几 辉煌棋牌app下载安装 胜负彩19177期最新奥盘 喜迎棋牌 股票入门基础知识书 连码三中三怎么样算中 湖南幸运赛车如何办理 炒股股市行情